"Knock us to our knees" meaning??

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Joined
Jun 23, 2015
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Student or Learner
Native Language
Thai
Home Country
Thailand
Current Location
Thailand
I just want to know this sentence "Knock us to our knees" ----- meaning?? Thank you in advance
 
Do you have a context for us?
 
Every challenge we take on has the power to knock us to our knees.
 
It means "has the power to defeat us".
 
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