It's difficult to imagine anything coming between them.

[diamondcutter]

It's difficult to imagine anything coming between them.

This is just a sample sentence from a Collins dictionary. In your native speakers’ eyes, does this sentence indicate that something has come between them?

 

[Rover_KE]

What word is being exemplified in the dictionary?

 

[diamondcutter]

imagine

 

[Rover_KE]

It's difficult to imagine anything coming between them.

... does this sentence indicate that something has come between them?

No.

 

[diamondcutter]

Does this sentence mean that the speaker can't imagine that something will come between them?

 

[emsr2d2]

It means exactly what it says. The speaker's opinion is that it's hard for them (and possibly anyone else) to imagine anything coming between two unspecified people.

 

[Tdol]

To me, it sounds like they are a couple who can get through the worst life has to throw at them.

 

[emsr2d2]

I would take it to mean that they are pretty much inseparable, probably as a couple, although it could refer to friends.